Summary

The Sgrò lab focuses on understanding the genetic basis of adaptation to environmental change using a range of approaches that include comparisons of populations collected from along latitudinal gradients, experimental evolution, quantitative genetics and genomics: genome-wise association studies, RNA sequencing, etc.

Related entries

Publication Citations

• Arthur, A. L., Weeks, A. R. and Sgrò, C. M., 'Investigating latitudinal clines for life history and stress resistance traits in Drosophila simulans from eastern Australia', Journal of Evolutionary Biology, vol. 21, no. 6, 2008, pp. 1470-1479. http://dx.doi.org/10.1111/j.1420-9101.2008.01617.x. Details
• Kellermann, V., van Heerwaarden, B., Sgrò, C.M. and Hoffmann, A.A., 'Fundamental evolutionary limits in ecological traits drive Drosophila species distributions', Science, vol. 325, 2009, pp. 1244-1246. http://www.sciencemag.org/content/325/5945/1244.long. Details
• Lee, Siu F., Sgrò, Carla M., Shirriffs, Jennifer, Wee, Choon W., Rako, Lea, van Heerwaarden, Belinda, and Hoffmann, Ary A., 'Polymorphism in the couch potato gene clines in eastern Australia but is not associated with ovarian dormancy in Drosophila melanogaster', Molecular Ecology, vol. 20, no. 14, 2011, pp. 2973-2984. http://dx.doi.org/10.1111/j.1365-294X.2011.05155.x. Details
• Sgrò, Carla M., van Heerwaarden, Belinda, Kellermann, Vanessa, Wee, Choon W., Hoffmann, Ary A., and Lee, Siu F., 'Complexity of the genetic basis of ageing in nature revealed by a clinal study of lifespan and methuselah, a gene for ageing, in Drosophila from eastern Australia', Molecular Ecology, vol. 22, no. 13, 2013, pp. 3539-3551. http://dx.doi.org/10.1111/mec.12353. Details
• van Heerwaarden, B. and Sgrò, C. M., 'The effect of developmental temperature on the genetic architecture underlying size and thermal clines in Drosophila melanogaster and D. simulans from the east coast of Australia', Evolution, vol. 65, no. 4, 2011, pp. 1048-1067. http://dx.doi.org/10.1111/j.1558-5646.2010.01196.x. Details

See also

• Bechsgaard, Jesper S., Hoffmann, Ary A., Sgró, Carla, Loeschcke, Volker, Bilde, Trine, and Kristensen, Torsten N., 'A comparison of inbreeding depression in tropical and widespread Drosophila species', PLoS One, vol. 8, no. 2, 2013. http://dx.doi.org/10.1371/journal.pone.0051176. Details
• Hoffmann, A.A. Ratna, E. Sgrò, C.M. Barton, M. Blacket, M. Hallas, R. De Garis, S. Weeks, A.R., 'Antagonistic selection between adult thorax and wing size in field released Drosophila melanogaster independent of thermal conditions', Journal of Evolutionary Biology, vol. 20, no. 6, 2007, pp. 2219-2227. http://dx.doi.org/10.1111/j.1420-9101.2007.01422.x. Details
• Hoffmann, A.A., Sgrò, C.M. and Weeks, A.R., 'Chromosomal inversion polymorphism and adaptation', Trends in Ecology and Evolution, vol. 19, 2004, pp. 482-488. http://dx.doi.org/10.1016/j.tree.2004.06.013. Details
• Hoffmann, Ary A. and Sgrò, Carla M., 'Climate change and evolutionary adaptation', Nature, vol. 470, no. 7335, 2011, pp. 479-485. http://dx.doi.org/10.1038/nature09670. Details
• Kellermann, V. M., Van Heerwaarden, B., Hoffmann, A. A. and Sgrò, C. M., 'Very low additive genetic variance and evolutionary potential in multiple populations of two rainforest Drosophila species', Evolution, vol. 60, 2006, pp. 1104-1108. http://dx.doi.org/10.1111/j.0014-3820.2006.tb01187.x. Details
• Kellermann, V.M. Hoffmann, A.A. Sgrò, C.M., 'Hsp90 Inhibition and the Expression of Phenotypic Variability in Rainforest Species Drosophila birchii', Biological Journal of the Linnean Society, vol. 92, 2007, pp. 457-465. http://dx.doi.org/10.1111/j.1095-8312.2007.00875.x. Details
• Kristensen, T.N., Loeschcke, V., Bilde, T., Hoffmann, A.A., Sgrò, C., Noreikiene, K., Ondresik, M. and Bechsgaard, J., 'No inbreeding depression for low temperature developmental acclimation across multiple Drosophila species', Evolution, vol. 65, no. 11, 2011, pp. 3195-3201. http://dx.doi.org/10.1111/j.1558-5646.2011.01359.x. Details
• Mitchell, Katherine A., Sgrò, Carla M., and Hoffmann, Ary A., 'Phenotypic plasticity in upper thermal limits is weakly related to Drosophila species distributions', Functional Ecology, vol. 25, no. 3, 2011, pp. 661-670. http://dx.doi.org/10.1111/j.1365-2435.2010.01821.x. Details
• Rako, L., Anderson, A.R., Sgrò, C.M., Stocker, A.J. and Hoffmann, A.A., 'The association between inversion In(3R)Payne and clinally varying traits in Drosophila melanogaster', Genetica, vol. 128, 2006, pp. 373-384. http://dx.doi.org/10.1007/s10709-006-7375-7. Details
• Sgrò, C. M. Hoffmann, A. A., 'Genetic correlations, trade-offs, and environmental variation', Heredity, vol. 93, 2004, pp. 241-248. http://dx.doi.org/10.1038/sj.hdy.6800532. Details
• Sgrò, C. M., Magiafoglou, A., Faine, L. and Hoffmann, Ary A., 'Absence of clinal variation in virgin retention capacity in Australian Drosophila melanogaster', Evolutionary Ecology Research, vol. 20, 2006, pp. 407-413. http://dx.doi.org/10.1007/s10682-006-0010-3. Details
• Sgrò, C. M., Milton, C. C., Jensen, L. T., Frydenberg, J., Loeschcke, V., Batterham, P., and Hoffmann, A. A., 'Nucleotide diversity in the Hsp90 gene in natural populations of Drosophila melanogaster from Australia', Insect Molecular Biology, vol. 17, no. 6, 2008, pp. 685-697. http://dx.doi.org/10.1111/j.1365-2583.2008.00843.x. Details
• Sgrò, C. M., Overgaard, J., Kristensen, T. N., Mitchell, K. A., Cockerell, F. E., and Hoffmann, A. A., 'A comprehensive assessment of geographic variation in heat tolerance and hardening capacity in populations of Drosophila melanogaster from eastern Australia', Journal of Evolutionary Biology, vol. 23, no. 11, 2010, pp. 2484-2493. http://dx.doi.org/10.1111/j.1420-9101.2010.02110.x. Details
• Sgrò, C.M., Lowe, A.J. and Hoffmann, A.A., 'Building evolutionary resilience for conserving biodiversity under climate change', Evolutionary Applications, vol. 4, no. 2, 2010, pp. 326-337. http://dx.doi.org/10.1111/j.1752-4571.2010.00157.x. Details
• Sgrò, C.M., Wegener, B. and Hoffmann, A.A., 'A naturally-occurring variant of Hsp90 that is associated with decanalization', Proceedings of the Royal Society of Biological Sciences, vol. 277, 2010, pp. 2049-2057. http://dx.doi.org/10.1098/rspb.2010.0008. Details
• Telonis-Scott, M., Gane, M., De Garis, S., Sgrò, C.M. and Hoffmann, A.A., 'High resolution mapping of candidate alleles for desiccation resistance in Drosophila melanogaster under selection', Molecular Biology and Evolution, vol. 29, no. 5, 2012. http://dx.doi.org/10.1093/molbev/msr294. Details
• Telonis-Scott, M., van Heerwaarden, B., Johnson, T.K., Hoffmann, A.A. and Sgrò, C.M., 'New levels of transcriptome complexity at upper thermal limits in wild Drosophila revealed by exon expression analysis', Genetics, vol. 195, no. 3, 2013, pp. 809-830. http://dx.doi.org/10.1534/genetics.113.156224. Details
• Telonis-Scott, Marina, Hoffmann, Ary A., and Sgrò, Carla M., 'The molecular genetics of clinal variation: a case study of ebony and thoracic trident pigmentation in Drosophila melanogaster from eastern Australia', Molecular Ecology, vol. 20, no. 10, 2011, pp. 2100-2110. http://dx.doi.org/10.1111/j.1365-294X.2011.05089.x. Details
• van Heerwaarden, B., Kellermann, V., Schiffer, M., Blacket, M., Sgrò, C. M., and Hoffmann, A. A., 'Testing evolutionary hypotheses about species borders: patterns of genetic variation towards the southern borders of two rainforest Drosophila and a related habitat generalist', Proceedings of the Royal Society B: Biological Sciences, vol. 276, no. 1661, 2009, pp. 1517-1526. http://dx.doi.org/10.1098/rspb.2008.1288. Details