Grant New approaches for pest control and maintaining healthy environments under climate change

Australian Research Council, Australian Laureate Fellowship

Invertebrate Biology, Population and Ecological and Evolutionary Genetics
Alternative Names
  • (ARC ID)
Bio21 Molecular Science & Biotechnology Institute 30 Flemington Road, The University of Melbourne, Parkville VIC 3010, Australia


The project titled 'New approaches for pest control and maintaining healthy environments under climate change' was an Australian Laurette Fellowship project linking the Australian Research Council and the University of Melbourne. The Hoffmann Lab was granted $AUD 1.5M and the project commenced in 2010. The project aimed to identify the genetic and evolutionary mechanisms that insects use to deal with environmental changes and the processes that promote evolutionary resilience to safeguard environmental services. The expected outcomes were guidelines for sustainable agricultural production and biodiversity protection in threatened environments like the Australian Alps. The project is part of the Zoology field of research.

Publication Citations

  • Kennington, W Jason, and Hoffmann, Ary A, 'Patterns of genetic variation across inversions: geographic variation in the In(2L)t inversion in populations of Drosophila melanogaster from eastern Australia', BMC Evolutionary Biology, vol. 13, no. 100, 2013. Details
  • Lee, S.F., Chen Y., Reuter, C., Vinti, G., Rane, R.V., Rako, L., Partridge, L. and Hoffmann, A.A., 'Polymorphism in the neurofibromin gene, Nf1, is associated with antagonistic selection on wing size and development time in Drosophila melanogaster', Molecular Ecology, vol. 22, no. 10, 2013, pp. 2716-2725. Details
  • Sgrò, Carla M., van Heerwaarden, Belinda, Kellermann, Vanessa, Wee, Choon W., Hoffmann, Ary A., and Lee, Siu F., 'Complexity of the genetic basis of ageing in nature revealed by a clinal study of lifespan and methuselah, a gene for ageing, in Drosophila from eastern Australia', Molecular Ecology, vol. 22, no. 13, 2013, pp. 3539-3551. Details

See also

  • Hoffmann, A.A., 'Evolutionary limits and constraints', in Jonathan B. Losos, David A. Baum, Douglas J. Futuyma, Hopi E. Hoekstra, Richard E. Lenski, Allen J. Moore, Catherine L. Peichel, Dolph Schluter & Michael C. Whitlock (ed.), The Princeton Guide to Evolution, Princeton University Press, Princeton, 2014, pp. 247-252. Details
  • Hoffmann, Ary A. and Sgrò, Carla M., 'Climate change and evolutionary adaptation', Nature, vol. 470, no. 7335, 2011, pp. 479-485. Details
  • Kellermann, V., Overgaard, J., Loeschcke, V., Kristensen, T.N. and Hoffmann, A.A., 'Trait Associations across Evolutionary Time within a Drosophila Phylogeny: Correlated Selection or Genetic Constraint?', PLoS One, vol. 8, no. 8, 2013. Details
  • Kristensen, T.N., Loeschcke, V., Bilde, T., Hoffmann, A.A., Sgrò, C., Noreikiene, K., Ondresik, M. and Bechsgaard, J., 'No inbreeding depression for low temperature developmental acclimation across multiple Drosophila species', Evolution, vol. 65, no. 11, 2011, pp. 3195-3201. Details
  • Liefting, M., Hoffmann, A.A, and Ellers, J., 'Measuring the plasticity of developmental rate across insect populations; comment on Rocha and Klaczko (2012)', Evolution, vol. 68, no. 5, 2013, pp. 1544-1547. Details
  • Overgaard, J., Hoffmann, A. A., and Kristensen, T. N., 'Assessing population and environmental effects on thermal resistance in Drosophila melanogaster using ecologically relevant assays', Journal of Thermal Biology, vol. 36, no. 7, 2011, pp. 409-416. Details
  • Overgaard, J., Kearney, M. R. and Hoffmann, A. A., 'Sensitivity to thermal extremes in Australian Drosophila implies similar impacts of climate change on the distribution of widespread and tropical species', Global Change Biology, vol. 20, no. 6, 2014, pp. 1738-1750. Details
  • Overgaard, J., Kristensen, T. N., Mitchell, K. A. and Hoffmann, A. A., 'Thermal Tolerance in Widespread and Tropical Drosophila Species: Does Phenotypic Plasticity Increase with Latitude?', The American Naturalist, vol. 178, S1, 2011, pp. S80-S96. Details
  • Sarup, P., Sørensen, J.G., Kristensen, T.N., Hoffmann, A. A., Loeschcke, V., Paige, K.N., and Sørensen, P., 'Candidate genes detected in transcriptome studies are strongly dependent on genetic background', PLoS One, vol. 6, no. 1, 2011. Details
  • Schiffer, Michele, Hangartner, Sandra, and Hoffmann, Ary A., 'Assessing the relative importance of environmental effects, carry-over effects and species differences in thermal stress resistance: a comparison of Drosophilids across field and laboratory generations', Journal of Experimental Biology, vol. 216, no. 20, 2013, pp. 3790-3798.​jeb.085126. Details
  • Telonis-Scott, M., Gane, M., De Garis, S., Sgrò, C.M. and Hoffmann, A.A., 'High resolution mapping of candidate alleles for desiccation resistance in Drosophila melanogaster under selection', Molecular Biology and Evolution, vol. 29, no. 5, 2012. Details
  • Telonis-Scott, M., van Heerwaarden, B., Johnson, T.K., Hoffmann, A.A. and Sgrò, C.M., 'New levels of transcriptome complexity at upper thermal limits in wild Drosophila revealed by exon expression analysis', Genetics, vol. 195, no. 3, 2013, pp. 809-830. Details
  • Terblanche, J.S., Hoffmann, A.A., Mitchell, K.A., Rako, L., Le Roux, P.C., and Chown, S.L., 'Ecologically relevant measures of tolerance to potentially lethal temperatures', Journal of Experimental Biology, vol. 214, no. 222, 2011, pp. 3713-3725. Details