Summary

The Drosophila Clinal Data Collection contains data on populations along the eastern coast of Australia. This collection contains data for eight drosophilid species that have been collected by the Hoffmann lab and other research groups over a period of more than 15 years. Clinal patterns arise when there are continuous changes in traits or genes over space. Clinal variation therefore provides a powerful approach to identifying traits and genes associated with environmental variation. The wide range of climatic conditions along the eastern Australian coast represents an outstanding natural laboratory for the study of traits and genes that are associated with climatic adaptation. The Clinal Data Collection remains an excellent resource for understanding past and future evolutionary responses to climate change.

Related entries

Publication Citations

• Arthur, A. L., Weeks, A. R. and Sgrò, C. M., 'Investigating latitudinal clines for life history and stress resistance traits in Drosophila simulans from eastern Australia', Journal of Evolutionary Biology, vol. 21, no. 6, 2008, pp. 1470-1479. http://dx.doi.org/10.1111/j.1420-9101.2008.01617.x. Details
• Barker, J S F, 'Population structure and host-plant specialization in two Scaptodrosophila flower-breeding species', Heredity, vol. 94, no. 1, 2005, pp. 129-138. http://dx.doi.org/10.1038/sj.hdy.6800592. Details
• Barker, J S F, Frydenberg, J, González, J, Davies, H I, Ruiz, A, Sørensen, J G, and Loeschcke, V, 'Bottlenecks, population differentiation and apparent selection at microsatellite loci in Australian Drosophila buzzatii', Heredity, vol. 102, no. 4, 2009, pp. 389-401. http://dx.doi.org/10.1038/hdy.2008.127. Details
• Barker, J. Stuart F., 'Genetic history of a colonizing population: Drosophila buzzatii (Diptera: Drosophilidae) in Australia', Biological Journal of the Linnean Society, vol. 109, no. 3, 2013, pp. 682-698. http://dx.doi.org/10.1111/bij.12067. Details
• Collinge, J. E., Hoffmann, A. A. and McKechnie, S. W., 'Altitudinal patterns for latitudinally varying traits and polymorphic markers in Drosophila melanogaster from eastern Australia', Journal of Evolutionary Biology, vol. 19, no. 2, 2006, pp. 473-482. http://dx.doi.org/10.1111/j.1420-9101.2005.01016.x. Details
• Gockel, Julia, Kennington, W. Jason, Hoffmann, Ary, Goldstein, David B., and Partridge, Linda, 'Nonclinality of Molecular Variation Implicates Selection in Maintaining a Morphological Cline of Drosophila melanogaster', Genetics, vol. 158, no. 1, 2001, pp. 319-323. http://www.genetics.org/content/158/1/319.full. Details
• Griffiths, J. A., Schiffer, M., and Hoffmann, A. A., 'Clinal variation and laboratory adaptation in the rainforest species Drosophila birchii for stress resistance, wing size, wing shape and development time', Journal of Evolutionary Biology, vol. 18, no. 1, Cambridge University Press, 2005, pp. 213-222. http://dx.doi.org/10.1111/j.1420-9101.2004.00782.x. Details
• Hallas, Rebecca, Schiffer, Michele, and Hoffmann, Ary A., 'Clinal variation in Drosophila serrata for stress resistance and body size', Genetical Research, vol. 79, no. 2, Cambridge University Press, 2002, pp. 141-148. http://dx.doi.org/10.1017/S0016672301005523. Details
• Hoffmann, A. A., Blacket, M. J., McKechnie, S. W., Rako, L., Schiffer, M., Rane, R. V., Good, R. T., Robin, C., and Lee, S. F., 'A proline repeat polymorphism of the Frost gene of Drosophila melanogaster showing clinal variation but not associated with cold resistance', Insect Molecular Biology, vol. 21, no. 4, 2012, pp. 437-445. http://dx.doi.org/10.1111/j.1365-2583.2012.01149.x. Details
• Hoffmann, A. A., Hallas, R., Sinclair, C., and Mitrovski, P., 'Levels of variation in stress resistance in Drosophila among strains, local populations, and geographic regions: Patterns for desiccation, starvation, cold resistance, and associated traits', Evolution, vol. 55, no. 8, 2001, pp. 1621-1630. http://dx.doi.org/10.1111/j.0014-3820.2001.tb00681.x. Details
• Hoffmann, A. A., Scott, M., Partridge, L. and Hallas, R., 'Overwintering in Drosophila melanogaster: outdoor field cage experiments on clinal and laboratory selected populations help to elucidate traits under selection', Journal of Evolutionary Biology, vol. 16, 2003, pp. 614-623. http://dx.doi.org/10.1046/j.1420-9101.2003.00561.x. Details
• Hoffmann, Ary A. and Shirriffs, Jennifer, 'Geographic variation for wing shape in Drosophila serrata', Evolution, vol. 56, no. 5, 2002, pp. 1068-1073. http://dx.doi.org/10.1111/j.0014-3820.2002.tb01418.x. Details
• Hoffmann, Ary A., Anderson, Alisha and Hallas, Rebecca, 'Opposing clines for high and low temperature resistance in Drosophila melanogaster', Ecology Letters, vol. 5, 2002, pp. 614-618. http://dx.doi.org/10.1046/j.1461-0248.2002.00367.x. Details
• Kennington, W Jason, and Hoffmann, Ary A, 'Patterns of genetic variation across inversions: geographic variation in the In(2L)t inversion in populations of Drosophila melanogaster from eastern Australia', BMC Evolutionary Biology, vol. 13, no. 100, 2013. http://dx.doi.org/10.1186/1471-2148-13-100. Details
• Knibb, W. R., Oakeshott, J. G. and Gibson, J. B., 'Chromosome inversion polymorphism in Drosophila melanogaster. I. Latitudinal clines and associations between inversions in Australasian populations', Genetics, vol. 98, 1981, pp. 833-847. http://www.genetics.org/content/98/4/833.long. Details
• Kriesner, P., Hoffmann, A. A., Lee, S. F., Turelli, M., and Weeks, A. R., 'Rapid Sequential Spread of Two Wolbachia Variants in Drosophila simulans', PLoS Pathogens, vol. 9, no. 9, 2013. http://dx.doi.org/10.1371/journal.ppat.1003607. Details
• Lee, S.F., Chen Y., Reuter, C., Vinti, G., Rane, R.V., Rako, L., Partridge, L. and Hoffmann, A.A., 'Polymorphism in the neurofibromin gene, Nf1, is associated with antagonistic selection on wing size and development time in Drosophila melanogaster', Molecular Ecology, vol. 22, no. 10, 2013, pp. 2716-2725. http://dx.doi.org/10.1111/mec.12301. Details
• Lee, Siu F., Sgrò, Carla M., Shirriffs, Jennifer, Wee, Choon W., Rako, Lea, van Heerwaarden, Belinda, and Hoffmann, Ary A., 'Polymorphism in the couch potato gene clines in eastern Australia but is not associated with ovarian dormancy in Drosophila melanogaster', Molecular Ecology, vol. 20, no. 14, 2011, pp. 2973-2984. http://dx.doi.org/10.1111/j.1365-294X.2011.05155.x. Details
• Loeschcke, Volker, Bundgaard, Jørgen, and Barker, J S F, 'Variation in body size and life history traits in Drosophila aldrichi and D. buzzatii from a latitudinal cline in eastern Australia', Heredity, vol. 85, no. 5, 2000, pp. 423-433. http://dx.doi.org/10.1046/j.1365-2540.2000.00766.x. Details
• Magiafoglou, A., Carew, M. E. and Hoffmann, A. A., 'Shifting clinal patterns and microsatellite variation in Drosophila serrata populations: a comparison of populations near the southernborder of the species range', Journal of Evolutionary Biology, vol. 15, no. 5, 2002, pp. 763-774. http://dx.doi.org/10.1046/j.1420-9101.2002.00439.x. Details
• McKechnie, S. W., Blacket, M. J., Song, S. V., Rako, L., Carroll, X., Johnson, T. K., Jensen, L. T., Lee, S. F., Wee, C. W., and Hoffmann, A. A., 'A clinally varying promoter polymorphism associated with adaptive variation in wing size in Drosophila', Molecular Ecology, vol. 19, no. 4, 2010, pp. 775-784. http://dx.doi.org/10.1111/j.1365-294X.2009.04509.x. Details
• Mitrovski, Paul and Hoffmann, Ary A., 'Postponed reproduction as an adaptation to winter conditions in Drosophila melanogaster: evidence for clinal variation under semi-natural conditions', Proceedings of the Royal Society of Biological Sciences, vol. 268, 2001, pp. 2163-2168. http://dx.doi.org/10.1098/rspb.2001.1787. Details
• Rako, L., Poulsen, N. A., Shirriffs, J., and Hoffmann, A. A., 'Clinal variation in post-winter male fertility retention; an adaptive overwintering strategy in Drosophila melanogaster', Journal of Evolutionary Biology, vol. 22, no. 12, 2009, pp. 2438-2444. http://dx.doi.org/10.1111/j.1420-9101.2009.01852.x. Details
• Sgrò, Carla M., van Heerwaarden, Belinda, Kellermann, Vanessa, Wee, Choon W., Hoffmann, Ary A., and Lee, Siu F., 'Complexity of the genetic basis of ageing in nature revealed by a clinal study of lifespan and methuselah, a gene for ageing, in Drosophila from eastern Australia', Molecular Ecology, vol. 22, no. 13, 2013, pp. 3539-3551. http://dx.doi.org/10.1111/mec.12353. Details
• Umina, P. A., Weeks, A. R., Kearney, M. R., McKechnie, S. W., and Hoffmann, A. A., 'A Rapid Shift in a Classic Clinal Pattern in Drosophila Reflecting Climate Change', Science, vol. 308, no. 5722, 2005, pp. 691-693. http://dx.doi.org/10.1126/science.1109523. Details
• Weeks, A. R., McKechnie, S. W. and Hoffmann, A. A., 'In search of clinal variation in the period and clock timing genes in Australian Drosophila melanogaster populations', Journal of Evolutionary Biology, vol. 19, no. 2, 2005, pp. 309-656. http://dx.doi.org/10.1111/j.1420-9101.2005.01013.x. Details

See also

• Anderson, A. R., Hoffmann, A. A. and McKechnie, S. W., 'Response to selection for rapid chill-coma recovery in Drosophila melanogaster: physiology and life-history traits', Genetical Research, vol. 85, 2005, pp. 15-22. http://dx.doi.org/10.1017/S0016672304007281. Details
• Anderson, A. R., Hoffmann, A. A., McKechnie, S. W., Umina, P. A. and Weeks, A. R., 'The latitudinal cline in the In(3R)Payne inversion polymorphism has shifted in the last 20 years in Australian Drosophila melanogaster populations', Molecular Ecology, vol. 14, no. 3, 2005, pp. 851-858. http://dx.doi.org/10.1111/j.1365-294X.2005.02445.x. Details
• Bettencourt, Brian R., Kim, InYoung, Hoffmann, Ary A. and Feder, Martin E., 'Response to Natural and Laboratory Selection at the Drosophila HSP70 Genes', Evolution, vol. 56, no. 9, 2002, pp. 1796-1801. http://www.jstor.org/stable/3094738. Details
• Frydenberg, J., Hoffmann, A. A. and Loeschcke, V., 'DNA sequence variation and latitudinal associations in hsp23, hsp26 and hsp27 from natural populations of Drosophila melanogaster', Molecular Ecology, vol. 12, 2003, pp. 2025-2032. http://dx.doi.org/10.1046/j.1365-294X.2002.01882.x. Details
• Hoffmann, A. A., Shirriffs, J. and Scott, M., 'Relative importance of plastic vs genetic factors in adaptive differentiation: geographical variation for stress resistance in Drosophila melanogaster from eastern Australia', Functional Ecology, vol. 19, 2005, pp. 222-227. http://dx.doi.org/10.1111/j.1365-2435.2005.00959.x. Details
• Hoffmann, Ary A. and Harshman, Lawrence G., 'Desiccation and starvation resistance in Drosophila:patterns of variation at the species, population and intrapopulation levels', Heredity, vol. 83, 1999, pp. 637-643. http://dx.doi.org/10.1046/j.1365-2540.1999.00649.x. Details
• Hoffmann, Ary A., Clancy, David J. and Merton, Eve, 'Cytoplasmic Incompatibility in Australian Populations of Drosophila melanogaster', Genetics, vol. 136, no. 3, 1994, pp. 993-999. http://www.genetics.org/content/136/3/993.full.pdf. Details
• Kennington, W. Jason and Hoffmann, Ary A., 'The genetic architecture of wing size divergence at varying spatial scales along a body size cline in Drosophila melanogaster', Evolution, vol. 64, no. 7, 2010, pp. 1935-1943. http://dx.doi.org/10.1111/j.1558-5646.2010.00975.x. Details
• Lee, Siu F., Chen, Ying, Varan, Aiden K., Wee, Choon W., Rako, Lea, Axford, Jason K., Good, Robert T., Blacket, Mark J., Reuter, Caroline, Partridge, Linda, and Hoffmann, Ary A., 'Molecular basis of adaptive shift in body size in Drosophila melanogaster : Functional and sequence analyses of the Dca gene', Molecular Biology and Evolution, vol. 28, no. 8, 2011, pp. 2392-2402. http://dx.doi.org/10.1093/molbev/msr064. Details
• Overgaard, J., Kearney, M. R. and Hoffmann, A. A., 'Sensitivity to thermal extremes in Australian Drosophila implies similar impacts of climate change on the distribution of widespread and tropical species', Global Change Biology, vol. 20, no. 6, 2014, pp. 1738-1750. http://dx.doi.org/10.1111/gcb.12521. Details
• Overgaard, J., Kristensen, T. N., Mitchell, K. A. and Hoffmann, A. A., 'Thermal Tolerance in Widespread and Tropical Drosophila Species: Does Phenotypic Plasticity Increase with Latitude?', The American Naturalist, vol. 178, S1, 2011, pp. S80-S96. http://dx.doi.org/10.1086/661780. Details
• Paaby, Annalise B., Blacket, Mark J., Hoffmann, Ary A., and Schmidt, Paul S., 'Identification of a candidate adaptive polymorphism for Drosophila life history by parallel independent clines on two continents', Molecular Ecology, vol. 19, no. 4, 2010, pp. 760-774. http://dx.doi.org/10.1111/j.1365-294X.2009.04508.x. Details
• Sgrò, C. M., Magiafoglou, A., Faine, L. and Hoffmann, Ary A., 'Absence of clinal variation in virgin retention capacity in Australian Drosophila melanogaster', Evolutionary Ecology Research, vol. 20, 2006, pp. 407-413. http://dx.doi.org/10.1007/s10682-006-0010-3. Details
• Sgrò, C. M., Milton, C. C., Jensen, L. T., Frydenberg, J., Loeschcke, V., Batterham, P., and Hoffmann, A. A., 'Nucleotide diversity in the Hsp90 gene in natural populations of Drosophila melanogaster from Australia', Insect Molecular Biology, vol. 17, no. 6, 2008, pp. 685-697. http://dx.doi.org/10.1111/j.1365-2583.2008.00843.x. Details
• Sgrò, C. M., Overgaard, J., Kristensen, T. N., Mitchell, K. A., Cockerell, F. E., and Hoffmann, A. A., 'A comprehensive assessment of geographic variation in heat tolerance and hardening capacity in populations of Drosophila melanogaster from eastern Australia', Journal of Evolutionary Biology, vol. 23, no. 11, 2010, pp. 2484-2493. http://dx.doi.org/10.1111/j.1420-9101.2010.02110.x. Details
• Stocker, A. J., Foley, B. and Hoffmann, A. A., 'Inversion frequencies in Drosophila serrata along an eastern Australia transect', Genome, vol. 47, no. 6, 2004, p. 1144. http://dx.doi.org/10.1139/g04-078. Details
• Telonis-Scott, Marina, Hoffmann, Ary A., and Sgrò, Carla M., 'The molecular genetics of clinal variation: a case study of ebony and thoracic trident pigmentation in Drosophila melanogaster from eastern Australia', Molecular Ecology, vol. 20, no. 10, 2011, pp. 2100-2110. http://dx.doi.org/10.1111/j.1365-294X.2011.05089.x. Details
• Umina, P. A., Hoffmann, A. A., Weeks, A. R., and McKechnie, S. W., 'An independent non-linear latitudinal cline for the sn-glycerol-3-phosphate (α-Gpdh) polymorphism of Drosophila melanogaster from eastern Australia', Genetical Research, vol. 87, 2006, pp. 13-21. http://dx.doi.org/10.1017/S0016672306007919. Details
• van Heerwarden, B. and Hoffmann, A. A., 'Global Warming: Fly Populations Are Responding Rapidly to Climate Change', Current Biology, vol. 17, no. 1, 2007, pp. R16-R18. http://dx.doi.org/10.1016/j.cub.2006.11.035. Details
• Weeks, A. R., McKechnie, S. W. and Hoffmann, A. A., 'Robust clines and robust sampling: a reply to Kyriacou et al.', Journal of Evolutionary Biology, vol. 20, 2007, pp. 1652-1654. http://dx.doi.org/10.1111/j.1420-9101.2007.01355.x. Details